Southeast Iowa Vacation Packages 2025/2026 from $485

Southeast Iowa flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Cobblestone Inn & Suites - Fort Madison

$485

per person

Jan 2 - Jan 4

found 1 day ago

Roundtrip flight included

Chicago (ORD) to Burlington (BRL)

This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business center. There's a gym on site, and laundry facilities and free newspapers are also offered.

Top Southeast Iowa hotels deals

Cobblestone Inn & Suites - Fort Madison

4901 Avenue O, Fort Madison, IA

Free Cancellation

$74 nightly

$83 total

Nov 4 - Nov 5

Total with taxes and fees

Breakfast included

Parking included

The Catfish Bend Inn & Spa

3001 Winegard Dr, Burlington, IA

Free Cancellation

Reserve now, pay when you stay

$159 nightly

$178 total

Nov 17 - Nov 18

Total with taxes and fees

This smoke-free hotel features a casino, a full-service spa, and a water park. There's fun for all ages with a lazy river and a waterslide. Enjoy a meal in one of the 2 restaurants and free perks like free self parking and a roundtrip airport shuttle.

Pool

Spa

Comfort Suites Burlington

1780 Stonegate Center Dr, Burlington, IA

Free Cancellation

Reserve now, pay when you stay

$110 nightly

$123 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel features an indoor pool and a gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. A 24-hour business center, free WiFi in public areas, and a lobby fireplace are also on offer.

Pool

Hot Tub

Nauvoo Temple House Hotel

1200 Mulholland St, Nauvoo, IL

Free Cancellation

Reserve now, pay when you stay

$98 nightly

$111 total

Nov 9 - Nov 10

Total with taxes and fees

Free WiFi in public areas is available at this hotel. Take advantage of the free self parking.

Pet friendly

Parking included

Quality Inn & Suites Keokuk North

3404 Main St, Keokuk, IA

Free Cancellation

Reserve now, pay when you stay

$82 nightly

$92 total

Nov 23 - Nov 24

Total with taxes and fees

This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot tub and free perks like continental breakfast and free self parking.

Pool

Hot Tub

Baymont by Wyndham Keokuk

325 Main St, Keokuk, IA

Free Cancellation

Reserve now, pay when you stay

$66 nightly

$73 total

Nov 23 - Nov 24

Total with taxes and fees

An indoor pool is featured at this hotel, along with free self parking. Guests will appreciate free perks like on-the-go breakfast and WiFi in public areas. A safe deposit box is provided and the front desk is staffed around-the-clock.

Pool

Breakfast included

Don't see what you're looking for?

See all available properties in Southeast Iowa

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Snake Alley

Learn about the local history of Burlington when you take a trip to Snake Alley. Visit the area's casinos, or simply enjoy its bars.

Historic Nauvoo

Find out about the history of Nauvoo when you spend time at Historic Nauvoo. While you're in the area, stroll along the riverfront.

FunCity

Enjoy an outing to FunCity during your stay in Burlington. Visit the area's casinos, or simply enjoy its bars.

Frequently asked questions

How much are vacation packages to Southeast Iowa?

Packages, including flights and hotels in Southeast Iowa, start from as little as $485. Turn your travel fantasies into reality and begin your booking with Travelocity today.

Where can I get the best vacation package deals for Southeast Iowa?

Find your dream escape at Travelocity. With access to 400 airlines and a whopping 1,000,000 properties worldwide, creating the ultimate Southeast Iowa package deal couldn't be easier.

Why should I book my Southeast Iowa vacation package via Travelocity?

The three S's — savings, support and a stress-free booking — are just the tip of the iceberg. Enjoy a fulfilling travel experience knowing you can rely on our expert team of customer support professionals 24/7. With the Travelocity Price Match Guarantee, you can relax knowing you're getting the best deal available.

Will I save money on my Southeast Iowa car rental if I book it with a hotel or flight?

Sure can. And our Southeast Iowa vacation packages are the perfect way to do it. With only a few clicks you can save cash as well as time by combining your bookings. Pick up the keys to your rental car then chart your own course. Looking for things to do? Add some activities or experiences to your package and save on those too.

Which airport is best for Southeast Iowa?

Southeast Iowa is serviced by two main hubs — Quincy Regional-Baldwin Field Airport (UIN) and Southeast Iowa Regional Airport (BRL).

What is there to do in Southeast Iowa?

Southeast Iowa boasts hidden gems around every corner, however ensure you get to Catfish Bend Casino and Iowa State Penitentiary during your stay. These landmarks are popular with visitors.